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Integrins are cell surface adhesion molecules that link the ECM to the intracellular actin cytoskeleton.
Varying the metals and the organic molecules that link them can produce materials with a wide variety of properties.
Many receptors, such as those used in this work, do not activate the cell unless they bind molecules that link to multiple receptors simultaneously, and cause them to aggregate together in large signaling clusters.
We also discuss the use of engineered peptides as chimeric molecules that link solid recognition ability to the existing repertoire of bioactive peptides, integrin-binding domains, as well as proteins, eg, green fluorescence, protein to monitor mineralization.
This might provide clues about the molecules that link Mena with Rac1.
In another example of how this 3-component system can be employed for functional cloning, we expressed low levels pro-Caspase-10 and high levels of Fas, then screened cDNA libraries to clone adaptor molecules that link Fas to Caspase-10 (Figures S12 S15).
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The subsequent use of conventional high molecular weight (HMW) sheared genomic DNA creates a long range HAPPY panel (Mbp-sized DNA molecules) that links the shorter contigs obtained from the BAC panel into chromosome-wide contigs.
p62, an ubiquitin-LC3-binding protein, is one of the molecules that links the cargo, protein aggregates or organelles, to the vesicle-forming machinery (Kim et al., 2008; Pankiv et al., 2007).
We demonstrate that ISLO-1 acts as a novel adapter molecule that links the DAPC to SLO-1 in muscle.
Pyruvate is the molecule that links these two reactions.
Smad3 is an intracellular molecule that links the extracellular TGF-β signal with changes in gene transcription.
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