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Cyclodextrins are large cyclic molecules that improve the aqueous solubility of lipophilic compounds.
A more promising strategy may be to supplement mitochondria with molecules that improve their function.
These cytokines are either essential for attracting neutrophils directly or activate alveolar epithelial cells to express adhesion molecules that improve neutrophil infiltration.
This has been used to identify small molecules that improve survival of hiPSC motor neurons from ALS patients (Yang et al., 2013).
The behavioral phenotype of que mutants is robust and easily quantifiable; therefore, que mutants could be developed into a high-throughput system to screen libraries of compounds to identify small molecules that improve swimming behavior.
Finally, our work opens up an important new avenue for potential treatment development for UCMD, namely the search for molecules that improve or reduce membrane damage and myofiber disorganization.
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The massive diversification of life and its continual change is the result of small, imperfect mutations and changes at the scale of molecules that improved on ancestral solutions to problems.
We previously screened 640-compound natural-product library (NPL) for small molecules that improved phenotypes in models of protein misfolding and identified 5-fluorouridine (FU) as a hit (data not shown).
This finding probably can be explained by the presence of the copolymer that is highly hydrophilic and the MDP molecule that improves the self-etching technique [9].
The development of small-molecule drugs that improve CFTR processing (correctors) in patients with Phe508del mutations, which would be beneficial for the vast majority of patients with CF, has so far proven more difficult (reviewed in Bell et al).
One of the main disadvantages of carbon nanotubes is the lack of solubility in aqueous media, and to overcome this problem, scientists have been modifying the surface of CNTs, i.e., fictionalization with different hydrophilic molecules and chemistries that improve the water solubility and biocompatibility of CNT [67].
More suggestions(15)
genes that improve
chemistries that improve
composites that improve
pathways that improve
molecules that ameliorate
elements that improve
molecules that help
molecules that carry
molecules that differ
molecules that pass
molecules that build
molecules that give
molecules that target
molecules that average
molecules that interfere
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