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The term second messenger was coined upon the discovery of these substances in order to distinguish them from hormones and other molecules that function outside the cell as "first messengers" in the transmission of biological information.
Aptamers are small nucleic acid molecules that function as direct protein inhibitors, much like monoclonal antibodies.
The lipohilic/amphiphilic molecules that function as cellular activators or modulators of TRPC proteins span a wide range of chemical structures.
Fluorescent dyes based on small organic molecules that function in the near infrared (NIR) region are of great current interest in chemical biology.
The use of tissue penetrant near-IR wavelengths enables in vivo applications, however the design of molecules that function in this range remains a substantial challenge.
Diphosphoinositol pentakisphosphate kinase 2 (PPis5K2) is one of the mammalian PPIP5K isoforms responsible for synthesis of diphosphoinositol polyphosphates (inositol pyrophosphates; PP-InsPs), regulatory molecules that function at the interface of cell signaling and organismic homeostasis.
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(A) Such a molecule that functions as a molecular rotor driven by chemical energy [1].
Bacterial ribosomes stalled on defective messenger RNAs (mRNAs) are rescued by tmRNA, an ∼300-nucleotide-long molecule that functions as both transfer RNA (tRNA) and mRNA.
We show how a template-controlled reaction performed in the organic solid state can be used to construct a molecule that functions as an organic building unit of both a metal-organic polyhedron and polygon.
In this study, Moshitch-Moshkovitz et al. constructed a GFP (green fluorescent protein -Met chimeric molecule that functioned similarly to wild typrotein -Metd then generated GFP-chimericansgenic molecule
TNF-related apoptosis-inducing ligand (TRAIL) is an immune effector molecule that functions as a selective anti-tumor agent.
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particles that function
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molecules that help
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molecules that differ
molecules that pass
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molecules that build
molecules that target
molecules that average
molecules that interfere
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