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Antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses.
Some modern metabolism-based models of abiogenesis incorporate Oparin's enzyme-containing coacervates but suggest a steady progression from simple organic molecules to coacervates, specifically protobionts, aggregates of organic molecules that display some characteristics of life.
Less-clearly defined states of matter include plasmas, which are ionized gases at very high temperatures; foams, which combine aspects of liquids and solids; and clusters, which are assemblies of small numbers of atoms or molecules that display both atomic-level and bulklike properties.
We conclude that when the active repressors are controlled by corepressor molecules that display large ("coherent") number fluctuations or when corepressors can be irreversibly removed directly from promoter-bound repressors, the response in gene activity can become significantly sharper than without intrinsic noise.
Although TIMPs are compact molecules that display only limited conformational flexibility, backbone movement of TIMP-1 has been reported upon binding to MMP-3 [ 35].
To this end, we have identified the heterocyclic small molecules naringenin and flavone as small molecules that display the novel combined actions of IL-6-promoted STAT3 inhibitor and SOCS3-inducer in VECs.
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By using ligand based pharmacophore generation approach and virtual screening against natural products libraries we retrieved twenty unique molecules that displayed utmost binding affinity, least binding energies and effective drug properties.
The slight increase in standard error of the average size of PEGylated ConA could be due to the small percentage of ConA molecules that displays either low levels of PEGylation or no PEGylation at all.
Structurally, the fibronectin represents a prototypic ECM molecule that displays highly modular structure [ 13].
We are currently attempting to identify an endogenous lectin-like molecule that displays these properties.
An attribute of relevance to haemophilia is that the use of this cell line produces a rFIXFc molecule that displays human posttranslational modifications (PTMs) 23, 27.
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