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The Mme I product is ligated to a second branched linker ("B", inset), consisting of a pool of 16 different species of molecules that differ only at the 3" two nucleotide overhang.
Even molecules that differ by a single atom can vibrate quite differently.
We show classification with better than 99% accuracy for DNA hairpin molecules that differ only in their terminal Watson-Crick basepairs.
Thiol conjugates are produced by partial reduction of the interchain disulfides, followed by conjugation with a drug-linker, resulting in a heterogeneous mix of molecules that differ with respect to the site of conjugation and the number of drugs per antibody.
Each family consists of molecules that differ slightly from another.
Chemical structures of morphine and heroin: the parts of the molecules that differ are shown in green.
Similar(40)
As outlined for the phenylpropanoic acids, IMS also enabled rapid separations of very similar molecules that differed only by the presence or absence of a double bond.
The distinct P9 pocket electrostatic patterns were conserved both among molecules that differed at several amino acid sequence positions and between structures where residue 37 constitutes the only disparity (e.g., HLA-DRB1*03 01 HLA-DRB1*03 015).
In molecular morphing, a path of molecules (morphs) that differ only by small structural perturbations is constructed.
Even in identical molecules the number of base pairs that separate as function of time varies as separation requires random thermal activations that differ in different identical molecules.
Length heteroplasmy (LH) describes the co-existence of at least two populations of mitochondrial (mt DNA molecules in a DNA extract that differ in the number of nucleotides and therefore in their length.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com