Sentence examples for molecules that combine from inspiring English sources

We hypothesized that hybrid molecules that combine apoptosis-dependent and apoptosis-independent mode of actions in a single molecule may lead to enhanced antitumor activity.

The structure of LHA at 2.6 Å reported here provides an understanding of the structural implications and challenges of engineering therapeutic molecules that combine functional properties of LHn of BoNTs with specific ligand partners to target different cell types.

Genetic engineering has led to the development of fusion protein toxins, which are targeted effector molecules that combine a targeting ligand such as a growth factor with a cytocidal moiety such as a plant or bacterial toxin.

Another exciting recent strategy involves the development of single-peptide molecules that combine differing modes of action.

Desensitization and endocytosis of G-protein-coupled receptors following the agonist binding are mediated by β-arrestins, which function as adaptor molecules that combine E3 ubiquitin ligases with the receptors to ubiquitinate the receptors (Shenoy and Lefkowitz, 2011).

Here we report a rapid access to small molecules that combine benefits of TB and dicarboxylic quinolines (DCQs).

Considering the structural and functional similarity of EC and 15d-PGJ2, we also tested a series of chimeric molecules that combined features of EC and 15d-PGJ2, the synthesis of which is described in detail elsewhere (Egger et al, 2014).

Here we design AK04, a molecule that combines the pharmacophore chlorambucil with that of STI-571 (Gleevec™).

The use of a novel engineered molecule that combines thyroid hormone and glucagon to target liver and adipose tissue might provide a new 'magic bullet' with exciting future prospects.

(131 I-CLR1404 is a small molecule that combines a tumor-targeting moiety with a therapeutic radioisotope.

The product of ITGAM, integrin-αM (CD11b+), is a molecule that combines with integrin-β2 to form a leukocyte-specific integrin.