Sentence examples for molecules that attenuate from inspiring English sources
There is a need to develop safer molecules that attenuate tumour progression without adversely affecting the overall quality of life.
Aggregation of the amyloid-β protein (Aβ) plays a pathogenic role in the progression of Alzheimer's disease, and small molecules that attenuate Aβ aggregation have been identified toward a therapeutic strategy that targets the disease's underlying cause.
Several molecules that attenuate HLMC secretion, including adenosine and β2-adrenoceptor agonists, increase intracellular cAMP.
Several molecules that attenuate HLMC secretion including PGE2, adenosine and β2-adrenoceptor agonists increase intracellular cAMP 24.
The structural differences in the GES-2 active site give rise to a tightly bound deacylating water molecule, and it is the abundance and nature of the hydrogen bonding interactions between the acyl-enzyme complex and this water molecule that attenuate its activation for deacylation and subsequently make this step less efficient in GES-2 when compared to GES-5.
Further studies are needed to isolate and characterize the astrocyte-derived signaling molecule that attenuated the A β-induced decrease in P-gp expression.
In conclusion, pentapeptide DYDYQ provides an ideal backbone for exosite-directed anticoagulant molecules that could attenuate or fully suppress α-thrombin formation in individuals with thrombotic tendencies.
In the context of TLR signaling, the tolerance phenomenon can be used as a tool for identification of signaling molecules that can attenuate the inflammatory response, revealing potential participants in immunomodulation.
It will be interesting to see if there are therapeutically relevant miRNA targets against the AT1R, aldosterone or one of their downstream effector molecules that can attenuate the hypertrophic response and the inflammation that occurs during the development of heart failure.
Therefore, it is important to identify molecules that regulate or attenuate complement-mediated inflammation.
'Chemical chaperones' are small molecules that have been shown to attenuate unfolded protein response activation.
