Sentence examples for molecules that activate from inspiring English sources

Thiazolidinediones (TZDs), a class of molecules that activate the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR γ) (Desvergne and Whali, 1999), promote association with the 9- cis retinoic X receptor to form functional heterodimers that recognise specific DNA response elements within target genes (Jude-Aubry et al, 1997; Reginato et al, 1998).

The circulating molecules that activate PI3K/AKT genes of breast cancer cells will also stimulate those active ones of bone cells, leading to the over expression of PI3K/AKT and abnormal proliferation of bone cells general metastasis of bone without cell migration.

Sirtris has come up with hundreds of molecules that activate the SIRT1 enzyme, which is produced by the mammalian homologue of sir2.

Mitochondria may be a source of molecules that activate complements during ischemia/reperfusion injury to myocardium, providing therewith a stimulus for infiltration of polymorphonuclear leukocytes.

In animals, alkamides and N-acylethanolamides act as endogenous signaling molecules that activate cannabinoid receptors, which are coupled to signal transduction cascades involving glutamate and nitric oxide.

A third project uses photo-crosslinking and other biochemical methods to characterize plant proteins that play a direct role in recognizing the conserved bacterial molecules that activate the early plant immune system.

TGF- β-activated kinase-1 is an important signalling molecule that activates numerous signal transduction pathways, many of which are associated with cancer.

The researchers found that they could also boost regeneration with a molecule that activates the same metabolic switch.

However, the molecule that activates Smad1 in glomerulonephritis has not been fully elucidated.

One such protein is M2, a murine gammaherpesvirus 68-encoded molecule that activates the Vav1/Rac1 pathway via the formation of trimolecular complexes with Scr family members.

In this latter case, it is counterintuitive that loss of function mutations in a molecule that activates pro-inflammatory pathways can result in the increased inflammatory conditions seen with Crohn's disease.