Sentence examples for molecules shift the from inspiring English sources

When applied at nanomolar concentrations on live cells, these cell-penetrant molecules shift the O-GlcNAc equilibrium toward hyper-O-GlcNAcylation with EC50 values down to 3 nM and are thus invaluable tools for the study of O-GlcNAc cell biology.

Dietary supplementation of pregnant dams with methyl donor molecules shifts the phenotype of Avy offspring towards pseudoagouti, and this effect has been attributed to an increase in methylation at the allele [17], [20].

Binding of these inhibitors to KRAS at the switch-I and switch-II regions of the molecule shifts the preference to GDP rather than GTP impairing RAF binding.

Analogously, it can be observed the reduction of absorbance associated with the color of MB at λ = 664 nm (Fig. 10B) caused by the photo-oxidation of the MB molecule, shifting the absorption peaks to lower wavelength (blue shift).

This is the first demonstration that targeting this anti-apoptotic mechanism by an exogenous molecule shifts the balance towards apoptosis.

However, when the Fab molecules are structurally aligned a comparison of the bound BMPR-IA ectodomains shows that the receptor molecules shift slightly in the four complexes in the asymmetric unit (Fig. 1C F).

Fourier Transform infrared (FT-IR) patterns showed that in the MTPSC the C O groups of starch molecules shifted to the higher wavenumber, while the reactive hydroxyl groups of MMT shifted to the lower wavenumber.

In the mature caspase, steric clashes with the bulkier H266 on β-strand 8 disrupt a conserved network of water molecules and shift the neighboring Y195 (β-strand 7) toward T140 in helix 3.

The first, exemplified by insulin glargine, has been to modify the molecule to shift the isoelectric point.

The material excluded from column porosity is concentrated in the heptane-insoluble fraction; the peak of this fraction corresponding to smaller molecules shifted to earlier times than was found for the whole sample.

Therefore it represents a promising target for small molecule inhibitors to shift the apoptotic threshold in cancer cells after treatment with standard chemotherapy.