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From the M-P link map, we found that there were 71 small molecules shared by three cancers from GSE5364.
PAMPs are highly conserved molecules shared by many microorganisms of a particular class, such as LPS in gram-negative bacteria which can respond to TLR4.
Upon recognition of molecules shared by groups of related microbes (called pathogen-associated molecular patterns; PAMPs) by pattern-recognition receptors (such as the Toll-like receptors; TLRs), innate immune cells can initiate an inflammatory response.
The method was based on the identification of at least one consistent path between the candidates (output) and the targets (input), via other molecules shared by the regulated reactions in the causality graph.
In the context of innate response, there are other mechanisms to recognize stress cells or non-self-cells, including activating and inhibiting molecules shared by NK, NKT, and T γδ lymphocytes [ 99].
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Vasoactive intestinal peptide (VIP) is a molecule shared by the neuroendocrine immune network and is considered to be a potential candidate for treatment of inflammatory and autoimmune diseases.
These molecules are shared by all cells in the medium.
Using MS analyzer, the ion currents evolutions of 16 molecule groups (shared by a m/z ratio) were followed as functions of temperature.
This difference was related to the fact that many links were created in the causality graph when a molecule was shared by many regulated reactions, and these links were propagated throughout the graph.
(Bacteria can exchange DNA in the form of plasmids, molecules that are shared by the microbes and allow them to survive inhibitory antibiotics).
CPF photodegradation products include the oxon and other bioactive molecules not necessarily shared by degradation of several other organophosphates (Bavcon Kralj et al. 2007).
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