We demonstrated that the colorectal cancer cells that acquire resistance to ICR62 also acquire resistance to treatment with other anti-EGFR mAbs such as cetuximab, but remain highly sensitive to treatment with small molecule pan-HER inhibitors.
We conclude that MAbs MRPm6 and MRPr1, together with MAb QCRL-1, which has previously been mapped to the heptapeptide 918SSYSGDI924, remain highly specific probes for detection of different regions of the MRP molecule.
Mesenchymal stem cells mixed in DnL gels and injected through a fine needle remain highly viable (>90%) during the encapsulation and delivery process, and encapsulated large molecules are released with profiles that correspond to gel erosion.
The polls remain highly controversial.
Democrats remain highly vulnerable on the economy.
Older cities remain highly segregated.
Yet banks remain highly indebted and highly interconnected.
The cable network assets remain highly valuable, however.
Critics, however, remain highly skeptical.
Both sides will remain highly cautious.
