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Pathogen-specific molecules recognized by PRRs are called pathogen-associated molecular patterns (PAMPs) (Chisholm et al. 2006; Zipfel 2008).
Typical examples of molecules recognized by the 1D expert system X-PERT [32] are shown in Fig. 4. Figure 4 Examples of structures identified with the aid of the X-PERT program [32].
These probes bear antibodies immobilized to their outer surfaces, and when placed in the central nervous system binds a proportion of the molecules recognized by the antibodies from the adjacent extracellular space.
For example, in analogy to pharmacology, nutrients can be considered as signaling molecules recognized by specific cellular sensing mechanisms.
PSMA molecules, recognized by the anti-PSMA mAb were induced to cluster at the cell membrane due to the binding of a goat anti-mouse IgG antiserum (Gam) added to cell cultures at 37°C for the indicated times.
Synergism is predicted using enhanced synergistic molecules recognized by EPN.
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However, the precise identity of this subset as well as the molecule recognized by this antibody have remained unknown.
Consistent with this view, there is a single amino acid difference between the human and murine BLyS proteins in the portion of the molecule recognized by the BR3 receptor [18], [22], [23], [36].
The serum-treated cells, but not cells held in serum-free conditions, became 2E12-positive (Fig. 1E), which pointed to the serum origin of the molecule recognized by the 2E12 antibody.
Furthermore, through epitope mapping, we identify two distinct epitopes on H5 HA molecule recognized by these rhAbs and demonstrate their potential to protect against a lethal H5N1 virus infection in a mouse model.
One key SV molecule recognized by these adaptors may be synaptobrevin (Salem et al, 1998).
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