Sentence examples for molecules per virion from inspiring English sources
When compared to standards of known dye concentrations, the 10,000 and 100,000 dye molecules per virion labeling conditions produced virions with fluorescence equivalent 60 and 600 IR800 molecules per virion.
The pIX protein is a structural component of the Ad that stabilizes hexon-hexon interactions; there are 240 pIX molecules per virion.
Recent cryoEM data from Buck et al. suggest a maximum stoichiometry of one L2 molecule per L1 pentamer or 72 L2 molecules per virion [15].
We speculate that it is difficult to detect binding of gp41 to the HIV particle due to the need of further optimization of this assay and/or the limited amount of gp41 molecules available on a single HIV virion (∼10 30 Env (gp120 and gp41) molecules per virion).
This number is significant because it is comparable to the ∼30 gp41 molecules per virion.
One of the main obstacles is the extremely low number of the molecules (i.e., only 21 54 gp120 molecules per virion in contrast to the approximately 1400 Gag molecules per virion).
SDS-PAGE and Coomassie staining-based densitometry indicated that each of the virus preparations contained an average of ∼22 molecules L2 per virion (data not shown).
As Pathak et al. estimated that on average there are 7 A3G molecules per HIV1Δvif virion when the virus is produced on PBMCs [55], the physiological concentration is [A3G]>130 µM.
Considering the purity of rNef preparation (i.e., 95%), the differences in the molecular weight between CAp24 and NefG3C-GFP, and that it was reported that HIV-1 particles incorporate approximately 5,000 molecules of CAp24 per virion [ 26], we calculated the presence of about 150 NefG3C-GFP molecules per VLP.
A possible explanation could be that while HIV contains approximately only 10 gp120 trimers per virion, HSV-2 virions have about 300 gD molecules that need to be neutralized by GRFT.
Virions do not usually package more than eight segments7 and each segment generally occurs once per virion.
