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Binding of just four porphyrin molecules per single QD was sufficient for total QD disaggregation.
From the temperature (T) dependence of total volume of gels, densities of the polymer and solvent (water) components, and stoichiometry, we evaluated (1) the volume of gels occupied by a single mean polymeric residue and associated water molecules (expressed in units of nm3), mean vsp gel), and (2) number of water molecules per single mean polymeric residue, mean Ns gel), from near 273 K to 323 K.
FKBP12.6 binds to RyR2 with a stoichiometry of four FKBP12.6 molecules per single RyR2 channel complex.
The enzyme has one of the highest turnover rates, converting millions of H2O2 molecules per single catalase molecule each second.
In fact, negatively stained electron micrographs of complexes from this fraction clearly show two Crm1 molecules per single particle, compared to images of Crm1 monomers alone.
It has been shown that, under normal conditions, there is one 8-oxoG molecule per 10 10 guanines in a genome, corresponding to thousands of 8-oxoG molecules per single cell.
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Future studies implementing such assays at greater numbers of loci and in more individuals, with more single molecules per individual, could provide mechanistic insights into loci influencing regional transmission rates in males.
In our experiments we used extremely high amounts of transposase mRNA (around 9 × 107 molecules per a single copy of transposon), therefore it may be reasonable to expect multiple "cut-and-paste" events before transposon will finally settle.
In contrast, AH vaults showed considerably higher AMB retention following post column separation with 1213 and 2071 molecules of AMB per single AH vault for the two conditions.
Control vaults showed low levels of drug retention of 264 and 431 molecules of AMB per single control vault for the two respective loading conditions.
Moreover, release of ACh from the dominating epithelial cell type is via transmembrane transport, as reviewed in the preceding chapter, and not via exocytosis that allows for release of approximately 10,000 molecules of ACh per single vesicle.
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