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HA can form many hydrogen bonds with surrounding water molecules owing to its abundant functional groups, such as hydroxyl and carboxylic groups.
Aptamers have been widely used for the detection of target molecules owing to their chemical stability, easy modification and remarkable specificity and affinity for various target molecules.
Cyclotides are topologically complex molecules owing to the unique combination of a head-to-tail cyclized backbone and a knotted arrangement of disulfide bonds.
In the case of the surfactant-added TMAH, crystallographic orientation dependent adsorption of the surfactant molecules (owing to varying hydrophobicity of the crystallographic planes) is employed to describe the significant reduction in the undercutting at convex corners.
Similarly, boron halides, including BF3 and BCl3, have been used as substitute probe molecules owing to the 2p1 electronic structure of boron that provides a powerful Lewis acid when shared with a halogen atom [5, 6].
Obviously, it could be explained by the reorientation of benzene molecules owing to increase its concentration in solution, and the more benzene is already adsorbed, the easier it is for additional amounts to become fixed as a result of hydrophobic interaction [52].
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The low docking score of these molecules owed to the relatively high charge density of the charged amino group and the corresponding high desolvation penalty.
The presence of unsaturation in the triacylglycerol molecule, owing to the presence of oleic, linoleic, and linolenic acid moieties, functions as the active site for various oxidation reactions.
The results showed that the extracellular matrix protein mindin is a very potent adjuvant molecule owing to its enhancement of both humoral and cell-mediated immune responses.
Therefore, at least in our magnetic tweezers experiment where some force is always being exerted on the molecule owing to the bead tethering (in contrast to the ensemble equilibrium binding described in the paragraph above), no measureable long-range secondary structure forms in the presence of SSB.
In that case, even single iodine incorporation on a tyrosine moiety in CDR might destroy the immunoreactivity of the MAb molecule owing to the bulkiness of the ion atom and/or change in pKa value of the tyrosine moiety (from 10.00 to 8.51).
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