From an analytical perspective, CGA molecules offer a challenge owing to the structural similarities and complexity of these compounds.
The (6,3 -layers of transition metals and 3,5-pyridinecarboxylate (3,5-PDC) containing terminal coordinated molecules offer a great potential for obtained porous frameworks via the "pillaring" approach.
Direct inhibition or disintegration of collagen fibrils by small molecules offer a therapeutic approach to prevent or treat the diseases related to fibrosis.
CD40 agonist and antagonist molecules offer a new therapeutic alternative which has the potential to generate anticancer effects by different mechanisms.
When coupled to the growing exploitation of fluorescence-based readouts in high throughput and high content screening, it is clear that fluorescent molecules offer a safer, more powerful and more versatile alternative to radioligands in molecular pharmacology and drug discovery.
Immunological assays which use antibodies to detect parasite molecules offer a fundamentally different approach to both PCR and light microscopy.
From one perspective, DNA molecules offer a compact storage mechanism for sequence information and, often, stored DNA samples contain substantial regions that are yet to be sequenced.
It demonstrates that ionic gelation of cationic chitosan molecules offers a flexible and easily controllable process for systematically and predictably manipulating particle size and surface charge which are important properties in determining gene transfection efficacy if the nanoparticles are used as non-viral vectors for gene delivery, or as delivery carriers for protein molecules.
Furthermore, the core/shell nanogel delivery system employed here is readily amendable to selective surface functionalization by a variety of targeting molecules, offers a protective environment for sensitive cargo, and shows excellent targeting uptake and delivery in serum containing medium.
Sequence-specific recognition of DNA by small organic molecules offers a potentially effective approach for the external regulation of gene expression and is an important goal in cell biochemistry.
