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Although cross-reaction events have been described between siRNAs and molecules of limited sequence similarity [ 6, 7], the determination of specificity routinely requires the identification of oligonucleotides that are identical in sequence only to the intended target.
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The opposing oxygenase activity of Rubisco results in the synthesis of phosphoglycolate, a molecule of limited use to most organisms.
During the process of aging, mtDNA increasingly accumulates somatic mutations through multiplication of damaged DNA molecules because of limited effectiveness of the reparative mechanisms.
The first coordination shell of a molecule is of limited size and usually comprises no more than 14 significant interactions with other molecules.
The CNS normally is in an immunologically quiescent state, due to deficient expression of MHC molecules, and limited entry of infiltrating T-cells into the brain parenchyma.
This property of these gaseous molecules by themselves is of limited therapeutic value in suppressing pre-eclampsia as illustrated by numerous NO studies (Johal et al., 2014).
Subsequently, these polyclonal cell lines that confirmed expression of Mamu-DR molecules were performed two rounds of limited dilution assays to obtain a stable monoclonal cell line that co-expresses DRα and DRβ chains simultaneously as our previous described.
Once in the air, rather than the gourmet meals and snazzy cocktail lounges of yesteryear, we pay exorbitant prices for stale sandwiches and tiny bottles of grain alcohol, whatever it takes to get us through the hellacious hours of turbulence as we compete with other passengers for limited molecules of oxygen.
The production of particles from bubble bursting may also be affected by the possibility of a concentration gradient as a function of depth in the artificial seawater, especially in the case of surfactant molecules with limited water solubility.
Due to the complexity of human biology, a bottom-up integrative approach combining data from different levels (genes, molecules, cells, organs, body, etc). is of limited help in understanding disease pathophysiology [42].
Due to the complexity of human biology, a bottom-up integrative approach combining data from different levels (genes, molecules, cells, organs, body, etc). is of limited help in understanding disease pathophysiology [ 42].
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