Sentence examples for molecules of apoptosis from inspiring English sources

Cd intoxication revealed increased levels of proinflammatory cytokines (TNF-α, IL1β and IFN-γ), reduced levels of cellular defense proteins (Nrf-2 and HO-1) and glucose transporter (GLUT-2 and GLUT-4) along with the enhanced levels of signaling molecules of apoptosis (cleaved Caspase-12/9/8 Caspase-12/9/8reas of Cd-intoxicated rats.

Caspases are proteases of the cysteine family, which are common signaling molecules of apoptosis.

ESA-mediated apoptosis is regulated by AIF, ERK, RIP1 and ROS, which are key molecules of apoptosis and necroptosis.

Mitophagy involves the selective removal of damaged mitochondria, subsequently decreasing ROS and cytotoxic molecules of apoptosis and thus, promoting cell survival [206], [207].

On the other hand, as caspases are essential effector molecules of apoptosis, assaying for cleaved caspases offers the detection of apoptosis in early stages.

The tumor suppressor p53 is a major regulatory molecule of apoptosis and cell cycle progression.

We also detected the expression of caspase 3, a key molecule of apoptosis signal pathway, in the MMH-R and MMH-RT cells.

TNF- α is involved in the initiation and promotion of the inflammatory pathway following UVB: it exerts pleiotropic effects, including modulation of cell adhesion molecules, promotion of apoptosis, and activation of lymphocytes [ 1].

NST-732 therefore represents a novel class of small-molecule detectors of apoptosis, with potential useful applications in imaging of the cell death process both in vitro and in vivo.

To elucidate the type of cell death induced by the SI molecules, several markers of apoptosis were evaluated.

For example, NF-κB is involved in the transcription of genes encoding proinflammatory cytokines, such as IL-8 and TNF-α, adhesion molecules, including intracellular adhesion molecule 1 (ICAM-1), molecules involved in regulation of apoptosis, such as B cell lymphoma 2 (Bcl-2), and growth factors, such as erythropoietin.