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Exact(18)
These authors argued that abiotically formed amphiphilic molecules, most likely, fatty acids of phosphorylated, branched polyprenol-like compounds [10, 12, 14, 18, 19], which may have enveloped the first cells, could not be as sophisticated as modern two-tail lipids.
The small size of the VHHs is particularly important for this application as it allows simultaneous binding of different VHHs to neighbouring molecules, most likely without steric hindrance.
The acylation and alkylation labeling methods are often used on small molecules, most likely with protecting groups present, so that only one reactive site is available in order to minimize side products.
Using the NSF-supported Kraken and Ranger supercomputers, researchers from University College London and Rutgers University determined the shape of a key protein involved in HIV infection in an individual patient and then ranked the drug molecules most likely to block the activity.
Interactions between the AA' loop from two adjacent IL-3 molecules most likely involve co-folding.
These three antibodies do not bind to wild-type human and porcine PrP molecules, most likely due to sequence inconsistencies in residues necessary for forming the antigen-antibody bond.
Similar(42)
The molecule most likely changed its conformation within the SET electrodes between both measurements resulting in a shift in the position of the degeneracy points (new positions: Vg=−0.3 and 1.7 V). Figure 3a shows a 3D plot of I versus Vg and T for Vsd=10 mV.
In addition, CA IX is a cell adhesion molecule, most likely involved in cell-to-cell communication; its binding site overlaps with the M75 epitope (Závada et al, 2000).
Unfortunately, the close packing of a symmetry-related molecule most likely affects the position of the peptide, and residues that affect K11 peptide hydrolysis (Phe4, Val5, and Leu15) are disordered in the structure.
We found that FADD was required for ATG5-mediated cell death and CASP8 activation, but was not necessary for the induction of autophagy indicating FADD acts as an adaptor protein linking a proapoptotic signaling molecule (most likely a caspase) to ATG5.
Among all biomaterials targeted for phage display selection, directly using whole cells as selection target has many advantages: 1) it needs no further information about cell surface molecules or purification of these molecules; 2) the surface molecules are most likely in their original state; 3) the selection stimulates the native binding environment where other macromolecules coexist.
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