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Such scaffolding molecules might differ on different blood vessel types, and the requirements for such factors might differ among different proteins forming amyloid.
The relative ranking of poses of different ligands is a more challenging task than binding mode prediction as the molecules might differ in size and chemical properties.
We also speculate that the groups of activated signaling molecules might differ between LFS and HFS.
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Because the pharmacodynamics and biodistribution of a small-molecule drug might differ from that of an enzyme, a SRT approach might provide benefit in tissues less accessible to ERT.
Another caveat when using de-adhesion forces to determine adhesion energy is that the molecules involved in contact formation might differ from the molecules involved in contact separation [ 31 ], and that thus the energy of adhesion might be different from the energy of de-adhesion (see above).
Since the transport properties of molecules that exhibit quantum interference differs significantly from that calculated for ordinary conjugated molecules, the inelastic properties might differ significantly as well.
Having confirmed the inhibitory activity of NKp44 also in pDCs stimulated with DNA immunocomplexes, we wondered whether NKp44 molecule expressed by pDCs might differ from that expressed by NK cells (where the same receptor activates NK cell functions), hypothesizing, for instance, differences in its intracytoplasmic tail.
We therefore explored whether these two isoforms had the same effect on MHC class I molecules and whether their effects might differ according to the cell type in which they are expressed.
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Because of inter-molecular interactions, the wavelengths of IR bands from solid C60 clusters might differ from those from gas-phase molecules and depend on the environment temperatures.
This structure suggests that residues on an entirely different face of the molecule are involved in dimer formation, which raises the possibility that the dimer interface of the protease might differ between noroviral strains.
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