Sentence examples for molecules might block from inspiring English sources
In 2000 Mitcheson et al published a seminal paper in PNAS giving a molecular insight into how structurally unrelated molecules might block the ion channel [12].
We propose that upregulation of sPD-1 molecules might block the PD-1/PD-L1 signaling pathway.
This could include the use of 'biospecific polymers' coated with anti-adhesive molecules or the use of agents which might block the expression of genes controlling biofilm formation for the most prevalent pathogens.
Further preliminary mechanism research suggested that molecule 7h could intercalate into calf thymus DNA to form a steady supramolecular complex, which might block DNA replication to exert the powerful bioactivities.
Both of these two active molecules 5c and 5g could effectively intercalate into calf thymus DNA to form compound−DNA complex respectively, which might block DNA replication to exert their powerful antimicrobial activity.
The active molecule 3c could effectively interact with S. aureus DNA to form 3c DNA complex through groove binding mode, which might block DNA replication to display their powerful antimicrobial activity.
Since the tête-à-tête between prion molecules and normal PrPC seems to be crucial for prion replication, molecular immunologist Anthony Williamson of the Scripps Research Institute in La Jolla, California, figured that keeping them physically apart might block the process.
Ang II increased ERK and Akt phosphorylation in the HG group, and benazepril could not completely block these responses, suggesting that other molecules might be involved in the progression of DN.
Small organic molecules might be able to enter the active site and thus block parts of it, which would result in changes in the overall activity and selectivity.
These, together with measured binding-specificity differences, suggest that there is a potential for the design of molecules that might selectively block the acyl-CoA binding site.
Small molecules of urea could pass through the membrane, while larger blood molecules might not.
