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Analytical ultracentrifugation (AUC) is a powerful technique to determine the global conformational changes in RNA molecules mediated by cations or small molecule ligands.
In conclusion, DOTAP is an active DC stimulator resulting in the activation of ERK and p38 and induction of chemokines, cytokines and co-stimulatory molecules mediated by appropriate amount of ROS.
This activity involves the dimerization of two receptor molecules mediated by the presence of the hormone and the generation of a macromolecular complex with co-regulators (reviewed in [5]).
The latter involves labeling the nick ends of the DNA fragments by labeled digitoxin molecules mediated by tdt transferase enzyme.
Among the downstream molecules mediated by TGF-β, connective tissue growth factor (Ctgf/Ccn2) and endothelin 1 (Edn1) play an essential role in this fibrotic response (Leask, 2008; Leask et al., 2009).
Subsequently, non-covalent interaction between PML molecules mediated by both the SIM and the RBCC motif (which contains a RING domain and is essential for PML dimerization) promotes the growth of concentrated PML networks.
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The unique aspect of cadherin-mediated signaling is that the clustering of cadherin molecules is mediated by the direct cell-cell contacts.
Secondly, the non-bonding character in the FMO of these molecules is mediated by their open shell singlet biradical nature in ground state, as revealed by the Spin-flip time dependent density functional theory analysis.
While a single thrombin:suramin complex was found in the asymmetric unit cell of the crystal, some of the crystallographic contacts with symmetrically related molecules are mediated by both the enzyme and the ligand.
The binding of the molecules is mediated by free radicals, present on the surface of the plasma-treated PET.
As described above, Neugebauer and colleagues showed that C. crescentus can grow on maltodextrins and that the transport of these molecules is mediated by the MalA TBDR [22].
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Justyna Jupowicz-Kozak
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