Sentence examples for molecules may modulate from inspiring English sources

We investigate possible mechanisms of how small molecules may modulate protein protein binding and discuss examples of new candidates for drug design.

Alterantively, the MHC molecules may modulate CD4+ T cells responses via phagocytosis and indirect presentation by antigen-presenting cells [11].

We speculate that other membrane-associated molecules may modulate CEACAM6 aggregation and signal transduction, although this aspect of CEACAM6 biology requires further study.

The adverse effects of TNF- α, IL-1 β, and interferon γ (IFN- γ) are prevented when β-cells are treated with anti-inflammatory cytokines (IL-4, IL-10, and IL-13), showing that these molecules may modulate insulin serum levels, which in turn affect metabolic control at different levels.

It has been reported that, in animal model of skin fibrosis, TGF-β was able to induce transcriptional activation of the ET-1 gene in dermal FBs [ 15], suggesting that these cells possess an active TGF-β/ET-1 axis and both these molecules may modulate fibrogenic responses.

The models incorporate the intrinsic noisiness of kinetics in small compartments, the details of the substrate transport process to the compartment (diffusion or active transport) and the presence of intra-compartmental molecules other than substrate molecules which may modulate the enzyme-catalyzed process e.g. inhibitors.

Other molecules that may modulate these events include CD2-associated protein (CD2AP) which participates in endocytosis of polycystin-2, while PIGEA-14 is involved in forward trafficking from the ER to the Golgi[51].

The concomitant presence of PECAM1 and β-catenin on endothelial cells of wound granulation tissue further supports the dynamic interaction between these two molecules, which may modulate the proliferation phase of angiogenesis [ 7, 16].

However, our findings suggest that MM cells themselves are being selected for clones with increased numbers of somatically mutated adhesion molecules that may modulate their interaction with bystander cells of the BM microenvironment, to promote anti-apoptotic or pro-proliferative properties, or to decrease dependency during tumor progression.

Some articles have also demonstrated that antidepressant treatment may modulate molecules associated with neurogenesis [ 45] such as brain-derived neurotrophic factor (BDNF) [ 57].

While RNA molecules in the sperm chromatin may modulate gene expression in the progeny [21], paternal inheritance of epigenetic information in the form of CpG methylation patterns that in turn direct the establishment of site-specific non-CpG methylation may be but one more example in this class of non-Mendelian heredity.