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It is worth noting however, that this technique does not tell us about the nature of the interaction, these molecules may interact either by hydrogen bonding or purely through hydrostatic bonding.
Phenyl molecules may interact with nucleotides by π π interactions, which are connected with stacking, commonly observed for adjacent nucleotides in DNA.
Docking studies with 1 3 into the crystal structure of human 11β-HSD1 reveal how the molecules may interact with the enzyme and cofactor and give further scope for structure based drug design in the optimisation of these series.
It is well known that the amine group on chitosan molecules may interact with Fe3O4[13].
From this server studies on R. stricta alkaloids, we observed that many of these molecules may interact with CYP2D6 or CYP3A4 as substrates.
To a lesser extent, Folding@home also tries to predict a protein's final structure and determine how other molecules may interact with it, which has applications in drug design.
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Through this GPI anchor, and presumably via some positively charged side-chains of the C-terminal domain, the CPM molecule may interact with the membrane in such a way that its active centre will face alongside, i.e. well suited to interact with other membrane-bound protein substrates or small peptides.
These results and our finding that TLR7 and TLR9 association with UNC93B1 is mutually exclusive suggest that each UNC93B1 molecule may interact with a single TLR.
Finally, recent evidence suggests that a putative L1-type cell adhesion molecule may interact directly with the Drosophila EGF receptor to inhibit its activity.
In order to search for alternatives to the sulfoxide moiety in the long side chain of pure antiestrogens, several molecules that may interact with water in a fashion similar to ICI164,384 were designed and it was found that compounds with the carboxy, the sulfamide, or the sulfonamide instead of the sulfoxide moiety also functioned as pure antiestrogens.
Since RNAi-mediated knock-down of TbUNC119 did not result in any characteristic phenotypes, we searched for molecules that may interact or associate with TbUNC119 using yeast two-hybrid analysis.
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species may interact
medications may interact
pathways may interact
molecules may lead
molecules may offer
molecules may be
molecules may push
molecules may contain
molecules may drive
molecules may regulate
molecules may stimulate
molecules may include
molecules may describe
molecules may exhibit
molecules may enhance
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