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As small drug-like molecules, it may be possible to tailor their properties precisely, using the standard pharmaceutical toolkit - structure- and ligand-based virtual screening, parallel synthesis, and medicinal chemistry - properly to explore their specificity and properties.
When these free radicals interact with biological molecules, it may cause cellular lipid peroxidation and DNA damage [ 9].
Nevertheless, given the complexity of these molecules, it may also be expected that some helminth glycoconjugates display immunostimulatory activities [ 11].
Noteworthy, for discovery of tumor-associated molecules, it may be beneficial to use a combination of various digital differential display procedures and experimental data on gene expression.
For nonreactive molecules, the chemesthesis threshold for a brief exposure is typically > 1 ppm; for reactive molecules it may be lower.
Because this shared epitope is found within the peptide-binding groove of these MHC class II molecules, it may confer the ability to selectively bind arthritogenic peptide sequences for presentation to auto-reactive T cells.
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When an antigen binds to a receptor molecule, it may or may not evoke an immune response.
"Since the apparent molecular weight of the subunits so obtained is found to be close to half that of the intact molecule, it may be further concluded that the subunits of the DNA molecule which are conserved at duplication are single, continuous structures.
As an example, to achieve the total synthesis of a moderately complex molecule it may require 100 times more reactions than appear in the final route, largely due to reactions not working as expected and requiring development, or a change in the route.
Our results suggest that MHCI may not only have neurobiological activity as a membrane-bound molecule, it may also affect local neurons as a soluble molecule in vivo.
In utilizing binding to a large receptor molecule, it may be important that the spike S1 domain also acts as a "spacer arm" holding the receptor far enough away from the three-fold axis of symmetry of the spike S2 domain to permit fusion core re-arrangement and subsequent membrane fusion.
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CEO of Professional Science Editing for Scientists @ prosciediting.com