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The popularity of LC/MS/MS systems for complex mixture analysis of thermally labile, biologically relevant molecules is largely attributed to "soft" nature of atmospheric pressure ionization techniques such electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) and atmospheric pressure photoionization (APPI).

Separation of small molecules is largely based on q/m ratio.

Glycation of the fibrinogen molecules is largely responsible for altered fibrin clot features found at elevated glucose levels (10, 11).

Together, these results suggest that the increased expression of endothelial cell surface adhesion molecules is largely responsible for the galectin-induced, cytokine-mediated cancer cell adhesion.

While CLIP analysis showed clear binding of Celf3 to the middle regions of Gomafu, FISH analysis indicated that the subnuclear distribution of these two molecules is largely different.

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In growing internodes of the axillary branch of sorghum, the tritium label initially provided in the fructose moiety of sucrose molecules was largely (81%) recovered in the fructose moiety, indicating that a large portion of sucrose molecules is not hydrolysed and resynthesized during radial transfer.

At low loadings, CO2 molecules are largely trapped with small mobility.

Structure, dynamics and function of biological molecules are largely determined by physical forces acting on and between the molecules.

The electrocatalytic activities of Pt deposited on the self-assembled carbon films toward the degradation of small organic molecules are largely dependent on the quantity of Pt and carbon.

For a given enzyme concentration and for relatively low substrate concentrations, the reaction rate increases linearly with substrate concentration; the enzyme molecules are largely free to catalyse the reaction, and increasing substrate concentration means an increasing rate at which the enzyme and substrate molecules encounter one another.

However, the enzymes and genes involved in the biosynthesis of these complex molecules are largely uncharacterized.

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