Exact(2)
This technology allows for efficient functionalization of complex molecules, including numerous pharmaceutical targets.
The BBB can exclude from the CNS many large molecules, including numerous medications.
Similar(58)
This appeared to cause the transcription factors associated with these pathways such as NF- κB to promote the expression of their transcriptional targets, including numerous molecules that are themselves involved in TNF- α/IL-6 signalling.
In humans, the cytosolic sulfotransferases (SULTs) catalyze regiospecific transfer of the sulfuryl moiety (–SO3) from 3′-phosphoadenosine 5′-phosphosulfate to thousands of metabolites, including numerous signaling small molecules, and thus regulates their activities and half-lives.
Additionally, our results indicate adhesome complexes as a whole, including numerous cell signaling molecules, are more important for maintained sarcomere structure than suggested by the limited number of individual components identified as mutated in patients with muscular dystrophies, such as the heterodimeric αβ integrins (3) and calpain 3 (4).
Numerous molecules, including growth factors, ECM and adhesion molecules play essential roles in pharyngeal arch artery and OFT morphogenesis.
HLA genes encode numerous molecules including the HLA class I and II molecules, which have immunological functions.
The lymphangiogenic process is regulated by numerous molecules, including the vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) family.
These domains interact with numerous molecules, including DNA damage-repair proteins and other proteins with a regulatory role in fundamental cellular processes (Deng and Brodie, 2000).
From the most significantly differentiated proteins, we identify numerous molecules, including STAT1, ISG15 and TAP1 that are positively associated with KSR1 expression in patient samples.
This role of endothelium is achieved through the presence of membrane-bound receptors for numerous molecules, including proteins, lipid transporting particles, metabolites and hormones, as well as through specific junction proteins and receptors that govern cell cell and cell matrix interactions [ 1, 2].
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