Sentence examples for molecules in common from inspiring English sources

When there were molecules in common to several programs, additional molecules were picked in order to get the closest to the desired n test.

To assess the degree of variation introduced by the repetitions, a pairwise comparison showed that successive repetitions had only 33 (±5) series in common, a value that rises to 321 (±17) when considering first two molecules in common and 673 (±20) for first molecules in common.

Suppose that there is a table, e, that is the first and only table originally constructed according to plan p from matter n′, which has all but a few molecules in common with matter n.

As shown in the Venn diagrams (Fig. 3), this method, when applied to only two or three programs, may generate a great number of common molecules, too big for the experimental tests, as for instance in the case of Cn, where there were 208 molecules in common between Surflex and Gold (14 + 39 + 21 + 134) or 53 molecules in common between Surflex, Gold and FlexX (14 + 39).

Given a reference molecule, a series of four molecules with decreasing similarity (that is, increasing distance) to the reference was generated by linking from one paper with activity data to another through molecules in common between both. Figure 1 illustrates the concept: M1 and M3 are similar according to our definition, as are the pairs M3 and M5, M5 and M7, M7 and M9.

Compared to a virtual screen, which assumes that actives are more similar to each other than to inactives, the new benchmarks are based upon different assumptions: namely, that within an assay molecules with similar activity tend to have similar structures, and that structural similarity decreases as one moves from one paper to another through molecules in common between both.

Furthermore, molecules with decreasing levels of similarity to a reference can be found by either ordering molecules in an activity table by their activity, or by considering activity tables in different papers which have at least one molecule in common.

An important issue arising from the electrophysiological studies pertains to the mechanisms by which leptin and insulin, through the increased production of a signaling molecule in common (i.e., PIP3), produce opposing electrical responses in POMC neurons.

Kaplan and George tried to identify what these molecules had in common, structurally, that allowed them to affect the brain in the same way.

With the exception of progesterone, all of these closely related biologically active molecules have in common a shortened side chain in ring D and, in some cases, an oxidized OH group on ring A. The individual molecules are synthesized on demand by the placenta in pregnant women, by the adrenal cortex, and by the gonads.

The more features two molecules have in common the more similar they are [28, 29].