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CLARITY preserves cells and molecules in brain tissue and makes them transparent so the molecules inside the cell can be imaged in 3-D.
The diffusion-weighted signal in dMRI reflects the diffusivity of water molecules in brain tissue and can be utilized to produce image-based biomarkers for clinical research.
The design of biocompatible fluorescent probes for targeting vital molecules in brain is highly desirable in recent years since various statistical studies conducted by World Health Organization point out the upcoming risk of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease.
We determined the effects of nano-TiO2 on the redox state and signal molecules in brain tissue of mice exposed to nano-TiO2 (i.p. for 14 days).
We used Diffusion tensor MRI (a technique used to image, in vivo, the diffusion of water molecules in brain tissue) to relate white matter integrity to measures of successful and unsuccessful picture naming.
A technique that has gained remarkable popularity in the past ten years as means for studying white matter integrity is Diffusion Tensor MRI (DTI), used to image, in vivo, the diffusion of water molecules in brain tissue.
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Antemortem events, such as anoxia or hypovolemia, affect the molecules in brains more profoundly than a prolonged postmortem interval at least up to 24 h [ 3, 15, 32, 34].
Single administration of mangiferin or in combination with known anticancer chemicals has shown the potential benefits of this molecule in brain, lung, cervix, breast and prostate cancers, and leukemia besides its antioxidant and anti-inflammatory properties.
When modeling diffusion of fluorescent Aβ1 42 I also assumed that there was no turn-over of this molecule in brain tissue.
SMS has been widely studied, with multiple mutations and the associated phenotypes comprehensively described as well as a vast amount of information on the importance of this molecule in brain development [ 22- 25].
We analyzed the mouse Representative Transcript and Protein Set for molecules involved in brain function.
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