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Research on microporous materials, hollow solids with channels and cavities that include small guest molecules, has advanced in fundamental and applied aspects during 1999 2000.
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The study of a class of small non-coding RNA molecules, named microRNAs (miRNAs), has advanced our understanding of many of the fundamental processes of cancer biology and the molecular mechanisms underlying tumor initiation and progression.
The study of neutrophil surface molecule functions and kinetics has advanced our understanding of the pivotal role of neutrophil 'connectivity' to their behavior and their ability to induce tissue damage through the release of damaging mediators.
In the seven years since its inception, Chorus has advanced two dozen molecules into development from discovery through early phase clinical study in patients.
Driehaus' pick has advanced 18%.
The ability to measure and manipulate single molecules has greatly advanced the field of biophysics.
In the last decade, the application of cell-penetrating molecules has been advanced by the use of peptides, which have proven efficient in aiding nonpermeant molecules to cross the cell membrane.
Several new molecules, such as ZD-4927 anDPC-42323, have advanced into clinical trials as oral agents.
Multiple molecules have been developed as TRPV1 antagonists, and some of these have advanced to human trials (e.g., refs (130) and (131)).
X-ray crystallography had just begun as a discipline in 1911, and had advanced relatively rapidly from simple salt crystals to crystals of complex molecules such as cholesterol.
Computational procedures have advanced to the stage where the role of the environment (for example, the water around enzyme molecules) can be incorporated.
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