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There's no way to turn off the sense of smell, short of keeping odor-causing molecules from reaching the body's receptor cells.
Fat coats the taste buds and prevents the offending molecules from reaching them; that's one reason salad dressings are popular around the world.
One important CMV protein prevents cellular HLA-1 molecules from reaching the cell surface, preventing recognition and destruction by CD8+ T lymphocytes [ 82].
Because macropore channels can be regarded as "transportation highways" of the pore network, blocking them prevents crude oil feedstock molecules from reaching the catalytically active domains.
A second problem is the presence of BBB, preventing many therapeutics, especially large and/or charged molecules, from reaching the brain and spinal cord to treat disorders of the CNS [ 13].
Based on our MD simulations we suggest then that cellohexaose actually inhibits the enzymatic activity, since upon entering and strongly binding to the catalytic pocket the cleaved substrate takes too long to leave and thereby prevents fresh substrate molecules from reaching the reaction site.
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The vaccine would stimulate production of antibodies that would latch onto nicotine molecules and prevent them from reaching the brain.
Anti-drug antibodies bind to drug molecules and prevent them from reaching the brain.
The brush-like layer consists of protective molecules that keep sticky mucus from reaching the cilia and epithelial cells, thus ensuring the normal flow of mucus.
Efforts have been made to produce antibodies against the nicotine molecule that prevents the drug from reaching neural receptors that produce the effects normally associated with smoking.
By means of cis interaction, self MHC class I molecules sequester Ly49 receptors, preventing them from reaching the NK - target cell synapse [20].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com