Sentence examples for molecules for targeting from inspiring English sources

USPIO can be further chemically modified, termed cross-linked iron oxide nanoparticles (CLIO), in order to attach new molecules for targeting purposes [56 58].

Since the fibrillogenesis of amyloid-β peptide 1 42 (Aβ1–42) peptide is considered as a major cause of neuronal degeneration, specific interest has been focused on aromatic molecules for targeting this peptide.

Discovery of small molecules for targeting protein-protein interfaces beholds enormous challenges and is accounted by various factors, namely, shape of typical protein-protein interface and flexibility of proteins among others.

Other conceivable molecules for targeting ovarian cancer cells include follicle-stimulating hormone receptor (FSHR) [ 17], intercellular adhesion molecule 1 (ICAM-1) [ 18], Müllerian inhibiting substance type II receptor (MISIIR) [ 19], and human epidermal growth factor receptor 2 (HER2) [ 20].

Molecular Insight Pharmaceuticals, Inc. has developed a series of I-labeled and 99mTc-labeled small molecules for targeting the extracellular domain of prostate-specific membrane antigen (PSMA), a target initially selected for the diagnostic assessment of primary and metastatic prostate cancer [ 12, 13].

The presence of high affinity receptors for bombesin (BN -like peptides on a wide variety of tumours prompted us to employ some of our powerful BN -likein releasing peptides(GRP) antagonists as carrier molecules for targeting cytotoxic agents to tumour cells (Nagy et al, 1997).

I compare the Drosophila method with the traditional targeting scheme in yeast and mouse mainly to show that the targeting mechanism as well as many aspects of the experimental design remain unchanged, and that the Drosophila scheme differs only in the way in which the donor molecule for targeting is generated.

The fact that CAIX represents an endogenous marker for cellular hypoxia with predictive potential and that it is easily accessible through its extracellular domain make carbonic anhydrase IX to an attractive molecule for targeting approaches.

Because of these properties it has become a widely used molecule for targeting cancer cells [ 2].

Several studies have focused on mannose residues as a pilot molecule for targeting macrophages.

Our results, along with those reported previously, confirmed the high potential of this molecule for targeting CSCs independently of an embryonic signature expression.