Sentence examples for molecules for presentation from inspiring English sources

There are several mechanisms proposed to explain how exogenously-derived antigens that have been phagocytosed or macropinocytosed may be processed and loaded on MHC I molecules for presentation.

Yet in vertebrates such complete degradation is inconsistent with the production of peptides of sufficient length (13 17 amino acids) to bind class II MHC molecules for presentation to T cells [2], [3].

The rationale of this selection was the length of peptides that are bound by HLA molecules for presentation to T-cell receptors, typically from 8 20 amino acids, with nine amino acids being the predominant length of class I peptides and the core of class II peptides [69].

The goal is to identify conserved sequences that function as epitopes recognized by human leukocyte antigen (HLA) molecules for presentation to CD8+ and CD4+ T cells that provide immunity against all influenza A virus subtypes and obviate the need for yearly vaccine update.

Peptides derived from endogenous intracellular proteins are generally bound by the MHC-I molecules for presentation, thus paving the way for cell cytotoxicity in cellular immunity.

Apart from a few polysaccharides that carry both positive and negative charges, most polysaccharides found in encapsulated bacteria and in polysaccharide vaccines cannot be processed and bound to major histocompatibility complex class II (MHC II) molecules for presentation to T-helper cells and are, therefore, considered T-independent antigens [ 25, 26].

Class I and II major histocompatibility complex (MHC), essential molecules for antigen presentation, are increased in the striatum and SN, respectively, of PD patients [14], [37].

CD74 plays a critical role in this process by influencing both the expression and peptide loading of MHC II molecules for antigen presentation.

Subsequent to the TLR-ligand interaction, APCs (mainly DCs) uptake and process vaccine antigens to be exposed on cell membrane surface in association to major histocompatibility complex (MHC) molecules for efficient presentation to adaptive immune cells [ 24].

MHC class I and II molecules are utilized for presentation to CD8+ and CD4+ T-cells, respectively.

MHC class I molecules are specialized for presentation of endogenously synthesized proteins, including self-proteins, to the TCR of CD8+ T-cells [ 47].