Sentence examples for molecules for development from inspiring English sources
Machine-learning models for activity prediction provide means for assessing the polypharmacology and side-effect liability of drug candidates, so that the medicinal chemist can make informed decisions and focus on the most promising molecules for development as future medicines.
These results suggest the feasibility of developing DH agonists that can be applied topically and suggest the identity of new lead molecules for development of additional topically-active DH analogs.
A primary cDNA expression library with a titer of 5.0 × 105 PFU mL−1 was constructed from mRNA extracted from larval Haemaphysalis qinghaiensis ticks in order to identify certain genes, which would then be used as candidate molecules for development of effective vaccines to control this parasite.
Our study demonstrates the critical role of HLA class II molecules for development of functional human T cells able to support immunoglobulin class switching and efficiently respond to vaccination.
However, most of these plants, represent a virtually unlimited reservoir of molecules, are not explored chemically and can constitute lead molecules for development of new antimalarial drugs.
Human sirtuin 2 (SisT2) is an attractive target molecule for development of drugs to treat neurodegenerative diseases and cancer, because SIRT2 inhibitors have a protective effect against neurodegeneration and an anti-proliferative effect on cancer stem cells.
The synthetic strategies used in the present work have potential to prepare a large number of compounds for further refinement of structures to obtain molecules suitable for development as antifungal drugs.
They are also important components of iron-acquisition systems and signaling molecules important for development.
Ann Baker of Accenture, a consultancy, says that most firms are nowhere near their goal of tripling the output of molecules for clinical development.
Right now, Bleximo is mostly looking at speeding up simulations of new materials and molecules for drug development.
These results provide new candidate molecules for the development of treatments against Chagas disease.
