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Currently, identification of novel and effective small molecules for cellular reprogramming remains very labor intense.
Biological ion channels are key molecules for cellular regulation and communication.
In Gram-positive bacteria, modified oligopeptides often serve as the signaling molecules for cellular communication with the cooperation of two-component systems.
ROS are important signalling molecules for cellular signal transduction.
Polyamines, essential molecules for cellular activity, are undoubtedly involved in tumour cell growth [ 128].
MAP kinases have been previously suggested as molecules for cellular signal transduction of altered gravitational forces [ 5, 41].
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Oxygen is a crucial molecule for cellular function.
Optoacoustic imaging correspondingly offers important advantages in small animal imaging, including the use of non-ionizing radiation, the versatile sensing of chromophoric molecules for probing cellular and sub-cellular function, good spatial resolution and, in analogy to ultrasound imaging, real-time operation [19 21].
To manipulate the many small molecules required for cellular function, cells regulate the uptake and the metabolism of these molecules.
Wnts are key components of the stem cell niche and are short range signaling molecules responsible for cellular decisions such as proliferation and differentiation.
Polyamines are ubiquitous molecules essential for cellular life whose intracellular concentration is tightly regulated and maintained in the millimolar range in all cell types [ 1].
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