Sentence examples for molecules failed to from inspiring English sources
Both in the experiments at the B3LYP/6-31G** B3LYP/6-31G**h the PM6 method, some moleveles fanded to converge in geometry optimization, or had an imaginary frequency, and with nothesed in the comPM6isons – 787 bonds were used.
These molecules failed to enhance CCL25 and CCL28 mRNA levels (data not shown).
During PrP biosynthesis a subset of molecules failed to translocate into the ER lumen and ended up in the cytosol [14], [15], because of an intrinsic inefficiency of the PrP signal sequence [16].
Thus, following internalization of apoptotic cells in vivo, splenic DCs remained quiescent, without altering their net balance of co-stimulatory/-regulatory molecules, failed to mature ex vivo, and did not exert bystander inhibitory effects on the phenotype of neighboring DCs without apoptotic cell fragments.
For another RTX toxin, Actinobacillus actinomycetemcomitans leukotoxin (Ltx) it was recently shown that cells that do not express lymphocyte-associated antigen-1 (LFA-1) receptor molecules failed to accumulate Ltx in their raft fractions [18], suggesting that the association of Ltx and LFA-1 within lipid rafts was essential for Ltx to be in rafts.
Two oxygen molecules failed to escape.
One-third of all molecules fail to make it through clinical trials because it becomes clear that they will not justify further investment.
Proteins represent an expanding class of therapeutics, but their actions are limited primarily to extracellular targets because most peptidic molecules fail to enter cells.
By contrast, instable molecules fail to elicit an immune response due to rapid T cell epitope destruction [15], [16].
Considering that human CD8 molecules fail to bind to murine MHC, the human CD8+ T cells in immunodeficient mice transplanted with only human CD34+ HSCs are not educated in the murine thymus.
Non-cytolytic mutant α-hemolysin molecules fail to elicit NLRP3-inflammasome signaling, demonstrating that the responses are not due to non-specific activation of this innate immune signaling system by bacterially derived proteins.
