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Hedgehog (Hh) proteins comprise a family of secreted signaling molecules essential for patterning a variety of structures in animal embryogenesis.
It is capable of capturing crisp, three-dimensional images of individual proteins, molecules essential for regulating human health.
We have shown that saposins, small molecules essential for the degradation of sphingolipids, are required for lipid binding to CD1d molecules in the endocytic pathway.
Furthermore, studies on genetically engineered animals, especially knockout and transgenic mice, have highlighted a number of molecules essential for liver development.
This mini-review describes a recently developed and tested set of approaches for identifying and characterizing molecules essential for branching morphogenesis and other developmental processes.
To understand the degree of solar UV stress on micro-organisms and/or molecules essential for life on the surface of Mars, we also calculated the biologically effective dose (BED) for T7 and Uracil in relevant wavelength regions at the Martian surface as a function of season and latitude, and discuss the biological survival rates in the presence of Martian solar UV radiation.
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Here, by employing an in utero electroporation-based method that enables genetic labeling and manipulation of ChCs in vivo, we identify DOCK7, a member of the DOCK180 family, as a molecule essential for ChC cartridge and bouton development.
Peering still further into the future, if we can achieve active control of the selective reaction of biologically active molecules in solution, one can imagine developing a medical procedure that, using a fibre optic probe in situ, destroys by controlled reaction a specific molecule essential for the progression of a disease.
Our findings suggest that this gene, named nodal, encodes a signalling molecule essential for mesoderm formation and subsequent organization of axial structures in early mouse development.
Cathepsin B is mainly expressed in antigen-presenting cells (APCs) and is involved in protein processing for presentation and is responsible for the degradation of the invariant chain (Ii), a chaperone molecule essential for major histocompatibility complex (MHC) class II molecules assembly and transport [2, 3].
Finally, using the Mac-1 (CD11b/CD18) as a counter-ligand, leukocytes ligate RAGE on vascular endothelium as an adhesion molecule essential for exiting the circulation into areas of inflammation [13].
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