Sentence examples for molecules especially the from inspiring English sources

These molecules, especially the class known as Proteolysis Targeting Chimera (PROTACs), represent a paradigm shift in chemical genetics, but their most tantalizing potential is as novel therapeutic agents.

This study is the first to report multiple cPKCγ-interacting proteins in HPC mouse brain and suggested that cPKCγ signaling molecules, especially the cPKCγ-synapsin pathway, might be responsible for HPC-induced neuroprotection against cerebral ischemic injuries of mice.

These molecules, especially the protein complexes, are extremely fragile and heretofore have never been observed in laser ablation without undergoing thermally driven fragmentation.

Nevertheless, the overall EF-domain sequences of STIM molecules, especially the Ca2+ ligands, appear to be similar to the consensus EF-domain Ca2+-binding sequence.

Co-occurring mutations preferentially occur in functionally related gene pairs, such as signaling transduction molecules, especially the activation signaling transduction molecules.

Adhesion molecules, especially the integrin family of proteins, have important roles in this stage.

The nematicidal activity was affected by the substituted position in the molecule, especially the substitution group on the alkyl chain.

It is assumed, that electronic characteristics of the molecular surface, like the electrostatic potential, represent the behavior of a molecule, especially the binding situation, in the active site.

Non-binding inhibitory antibodies reacted highly against the C-terminal end of the VAR2CSA molecule especially the highly polymorphic DBL6ε domain.

This spatial arrangement restrains the overall freedom of the molecule, especially the orientations of both atoms O1 and O2 of resorcinol.

We might also suggest that this C-terminal part of the G3 domain plays a role in the initial activation of T cells and, later, the rest of the molecule, especially the G1 domain, becomes the main target.