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As other T lymphocytes, activation of Treg requires that they recognize antigenic peptides presented by cell-surface expressed molecules encoded in the major histocompatibility complex (MHC).
On this basis, we and others advanced the notion of Ad targeting based on expression of secreted paracrine adapter molecules encoded in the vector genome as a means of retaining targeting capacity of conditionally replicating Ad vectors (CRAds) [29] [32].
This group provided evidence that RNA molecules encoded in the region may have tumour suppressor activity, but it is also probable that the high frequency of deletions may in part be attributable to the instability of the region.
Briefly, all antigens are carried to the cell surface by molecules encoded in the MHC.
MicroRNAs are small (~20 23 nucleotides) non-coding ribonucleic acid (RNA) molecules encoded in the genomes of many eukaryotes and viruses.
HLA-E and HLA-G are non-classical but peptide-dependent MHC I molecules encoded in the MHC I locus with low levels of heterogeneity compared to classical MHC I molecules.
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The synthesis of mycolactone, a potent immunosuppressive small molecule encoded in the pMUM plasmid, presumably gave a population of M. marinum cells the ability to persist in a place their generalist relatives could not.
On the basis of the gene expression analysis, we selected a set of candidate genes, including SDF-1, PTN, IGF2, Insulin-like growth factor binding protein 4 (IGFBP4), and EFNB1, and examined the role of molecules encoded by these genes in DA induction of hESC in vitro.
Molecules encoded by MHC are involved in self/non-self discrimination in vertebrates.
Molecules being encoded in a rotation-translation invariant way, there is no need to scan for the lag which would yield the maximum cross-correlation.
The structure of a molecule is encoded in a series of binary digits (bits) that represent the presence or absence of particular substructures in the molecule.
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