Sentence examples for molecules designed to target from inspiring English sources

SiRNA molecules, designed to target gene-specific sequences, were co-transfected with plasmid DNA into Chinese hamster ovary (CHO) cells.

The identification of structurally diverse SOS1 binding ligands may assist in the discovery of new molecules designed to target RAS-driven tumors.

Four different antibody molecules designed to target the CD47-SIRPα interaction in malignancy are currently being studied in clinical trials: Hu5F9-G4, CC-90002, TTI-621, and ALX-148.

Results obtained with RNA trans-splicing molecules designed to target the 3′ end of mouse titin and human dysferlin pre-mRNA transcripts indicated that trans-splicing of pre-mRNA generated from minigene constructs or from the endogenous genes was achieved.

ZR2003 is a type II of combi-molecule designed to target DNA and the epidermal growth factor receptor (EGFR) without requirement for hydrolysis.

In brief, these molecules were designed to target 396 human miRNAs (Sanger miRBase v 8.0) were chemically synthesized and transfected into hMSC using optimized transfection conditions.

Obatoclax is a small-molecule drug designed to target the antiapoptotic Bcl-2 family members to a proapoptotic effect.

Small molecule inhibitors designed to target signaling pathways regulating stem cell renewal and maintenance may increase efficacy of traditional therapies.

AP26113 is a synthetic and highly selective small-molecule inhibitor designed to target ALK.

A ∼300 -compound small molecule library designed to target protein tyrosine phosphatases, including DUSPs, was screened for their effects on intracellular growth of Salmonella in the same manner as applied in the siRNA screen.

By exploiting their modular structure, SINEUP molecules can be designed to target virtually any mRNA of interest, and thus to increase the production of secreted proteins.