Sentence examples for molecules could inhibit from inspiring English sources

All affibody molecules could inhibit IL-6 and PGE2 production in TNF-α-stimulated MH7A cells.

In conclusion, we demonstrated that affibody molecules could inhibit cell proliferation and the production of inflammatory mediators by blocking the Ras/Raf signal transduction cascade.

However, we demonstrated for the first time that an affibody targeting intracellular signal transduction molecules could inhibit cell proliferation and the production of inflammatory mediators.

First, it was recognized that certain small molecules could inhibit the activity of protein kinases [ 23].

Use of Cx43-ezrin interaction inhibitors (such as peptides, peptidomimetics and small molecules) could inhibit opening of gap junctions for example in cardiomyocytes, regulatory T cells or human placental trophoblasts.

A number of small molecules, which could inhibit the intrinsic tyrosine kinase activity of VEGFR, have been reported previously with a range of nanomolar potencies, specificities, and pharmacokinetic properties [ 15– 17].

An important discovery about TKIs was that certain so-called "small molecule" drugs could inhibit TK activity by competing with ATP for binding to the intracellular catalytic domain of receptor TKs, which produced inhibition of various downstream signaling cascades by autophosphorylation [13].

Intriguingly, when molecules that specifically could inhibit the GABRA2 gene (i.e., α2 silent RNA [siRNA]) were introduced into the central amygdala, even the P animals no longer demonstrated binge drinking for a short period of time, and this effect correlated with a significant reduction of α2 levels.

Thus, unlabeled haptens (unconjugated molecules) could not inhibit the HRP-labeled haptens (conjugated molecules) binding to bispecific antibodies when 1 Fab region was against the junction newly generated during conjugation.

They suggest that, for the MFS efflux systems, all molecules could potentially inhibit the active site; however, 5'-OCQA exhibits in both cases a substantially smaller interaction region showing less complementarity.

Thus, Eph/ephrin system has been considered as attractive targets for drug design, as targeting these molecules could simultaneously inhibit several aspects of tumor growth and progression [ 7- 11].