Sentence examples for molecules characterised by from inspiring English sources

Heterogeneous targets need adaptive drug molecules, characterised by the presence of flexible elements at specific locations that sustain a viable binding affinity against existing or expected polymorphisms.

The pore textures of the corresponding activated carbons were investigated using the adsorption isotherms of four probe molecules characterised by their increasing molecular diameters, namely CO2, N2, C6H6 and CCl4.

The most common approach, which we study in this paper, uses molecules characterised by 2D fingerprints, with the similarity between a reference structure and a database structure calculated using an association coefficient such as the Tanimoto coefficient [1, 8].

Hydroxypyrones and their close congeners, hydroxypyridinones, comprise several classes of molecules characterised by high synthetic versatility.

Note that the stable states with a high amount of YdaM molecules are characterised by a high level of c-di-GMP and a low level of YciR II and vice versa, in line with the stable states of the logical model (Fig. 2).

A typical serpin molecule is characterised by three β-sheets (A C), eight to nine α-helices (A H) and a reactive-centre loop (RCL).

The geometry of a Pbtl molecule can be characterised by two parameters, the torsion angle ϕ describing the ethyl rotation and the twist angle ω between the phenyl and pyrimidine rings [42] (Fig. 15a).

The three families of molecules were successively separated and characterised by LC ESI MS in positive full scan mode.

Recently, various studies have reported very efficient and selective small molecule inhibitors of c-Met, characterised by the indolin-2-one core structure, such as PH A665752 and Kirin (Christensen et al, 2003).

The molecules in the two databases were characterised by ECFC_6 fingerprints.

The crystal structure of piperidine is characterised by chains of molecules linked by NH…N hydrogen bonds which are disposed about a 21 axis running along b.