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Current studies have demonstrated that a variety of deregulated molecules can alter Hippo signaling, leading to the constitutive activation of the transcriptional activator YAP or its paralog TAZ.
In conclusion, we can state that H2S molecules can alter the conductance of the device considerably, and the sensor can be used, as an experimental senor.
Structural changes of local anesthetic molecules can alter the potency to inhibit NMDA receptor signaling and are independent of the local anesthetic (sodium-channel blocking) potency.
Proteins contain allosteric sites which, when bound to by small molecules, can alter a protein's conformation and ultimately affect the protein's activity.
We demonstrated that changes in the molecular profile and lateral organization of membrane molecules can alter charge distributions of the entire membrane.
In general, mutations in stems within stem-and-loop elements of RNA molecules can alter structural stability (Δ G).
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The concern arises from the fact that modifications to the structure of the insulin molecule can alter binding to the insulin IGF receptors, theoretically altering carcinogenicity.
Since modifications to the structure of the insulin molecule can alter binding to the insulin and IGF-1 receptors, this provides a theoretical basis for concern about potential carcinogenicity of insulin analogues.
In addition, senescent cells don't completely shut down; they continue to leak enzymes and other molecules that can alter their environment.
To identify components required for NLR-mediated immunity, we designed and carried out a chemical genetics screen to search for small molecules that can alter immune responses in Arabidopsis thaliana.
PKA activity is regulated by molecules that can alter cAMP levels, and hence by GPCRs, which regulate adenylate cyclase activity.
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