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In contrast with bacteria, whose interaction with the catalyst is limited to the external surface, methanol molecules can access the whole material surface.
Interestingly, a thicker "funnel-like" shape region within the membrane was identified from which molecules can access, for each monomer, to the surface clefts where the drug-binding sites are located.
The results indicated that adsorbate molecules can access and fill more efficiently the slit-shape pores than ellipsoidal pores, whereas the ellipsoidal pores create higher adsorption potential than slit-shape pores.
However, by observing the deformation maps for the periplasmic (Fig. 13B) and cytoplasmic (Fig. 13C) leaflets it could be identified two symmetrical membrane 'patches' with increased thickness, both having a funnel-like shape, from which molecules can access, for each monomer, to the surface clefts where the drug-binding sites are located.
The fluorescence observations are compatible with the Laurdan label residing in a more polar environment when polyunsaturated fatty acids are added to the lipid mixtures, suggesting that the lipid headgroups are less tightly packed, and more water molecules can access Laurdan.
As shown in Table 1, water molecules can access to the pore vestibules in the lipid head group regions, but not into the hydrophobic region due to the restraints for water during equilibration.
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Because of the unique way the enzyme engages RNA molecules, it can access folded strands generally invisible to other techniques.
These reactors are fairly uniform in diameter and while protected by AAOs, added particles, precursors, or molecules only can access the inside of the tubes.
While the new drugs are likely to consist of high concentrations of natural "super-molecules", you can access their health benefits now, in food or as supplements.
According to several authors, the small size of water molecules allows them to penetrate into the microporosity (radius <2 nm) of the C S H sheets, while nitrogen <span class="lh">molecules, which are relatively larger, can access mainly the mesoporous domain (radius >2 nm) and cover more completely all the anfractuosities in this domain.
Another explanation may be the delivery route of the therapeutic agent as small molecule catK inhibitors administered systemically can access areas such as subchondral bone that would be limited by intra-articular delivery of rAAV vector.
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