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They bind to target molecules by folding into 3D structures that can discriminate different chiral compounds.
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The serotonin receptor keeps the LSD molecule in place by folding over it, and sometimes, this pair of molecules hides away inside nerve cells.
A wide range of RNA molecules can form specific secondary structures by folding their primary sequences.
Hoernschemeyer diagram and swelling capacity test show a better selectivity of PS organogel to chlorinated molecules compared to ester, hydrocarbons and alcohols organic molecules by 80 184 folds.
Direct visualization by AFM confirms that the RNA molecules indeed fold into the designed structures (Fig. 2d, f).
Transfer RNA molecules are folded into a 'clover-leaf' secondary structure by intrastrand base pairing.
Herschlag, professor of biochemistry and senior associate dean for graduate education and postdoctoral affairs, has been awarded a multi-site project grant from the General Medicine Science Institute to study the principles by which RNA molecules fold into their biologically active structures.
PAGE analysis suggests that RNA molecules efficiently fold into the designed structures (Supplementary Fig. 6a).
The aberrant protein molecules are folded abnormally, which seems to endow them with their ability to cause disease.
Another way to say this is that they do not involve actual alteration of the DNA molecules -- just the way the molecules are folded.
Both DNA and RNA molecules can fold into particular shapes.
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