Sentence examples for molecules by altering from inspiring English sources

n-3 PUFAs indirectly reduce the production of cytokines, reactive oxygen species (ROS), and adhesion molecules by altering the expression of inflammatory genes.

Substrate methylation confers significant changes to the physiochemical properties of methyl acceptor molecules by altering their solubility, reactivity and interaction with cellular targets.

Symmank et al. ([2002]) reported several minor modifications of the surfactin molecule by altering surfactin synthetase.

We had constructed an immunogenic [α1hu]-RT1.Aa molecule by altering hypervariable α1-helical region (a.a. 51 90) of ACI (RT1.Aa) to WF (RT1.Au) sequences [20], [26].

Following phosphorylation, STAT forms dimers, translocates to the nucleus and organizes the response to the signalling molecule by altering gene expression [ 44].

Further modification of this molecule by altering the stereochemistry, or constraining the molecule by the addition of aromatic rings within the polyketide chain, could not further enhance this desirable phenotype (Guenin-Mace et al., 2015).

Recently, a T-cell based mechanism has been proposed to explain the dual effect of anti-TNF therapy in the treatment of autoimmune diseases in which TNF can function as a pro-inflammatory cytokine as well as an anti-inflammatory immunoregulatory molecule by altering the balance of regulatory T cells [ 11].

The formation of the physical aggregates occurs by a change in the hydration state of enzyme molecules and/or by altering the electrostatic constant of the solution.

The effects of tetanus toxin on neuropeptide expression recapitulate the effects of manipulating circuit activity by disrupting signaling molecules or by altering O2 levels.

6 They can be switched on or off through interactions with other proteins or small molecules or by altering their positions within the cell in relation to their substrates.

Regarding the structural demands, Poupaert et al. [8] observed that the anticonvulsant activity was decreased when the hydrogen bond formation ability of the phenytoin molecule was reduced by altering the hydantoin ring into succinimide and pyrrolidinone and when these rings were N-methylated.