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Other areas of interest include the phenotypic and functional characterization of T regulatory cells, the detection of new antigenic epitopes for the development of novel small molecules as possible immunotherapeutic agents, and the immune monitoring of T-cell responses in patients in clinical trials.
Typically, metabolomics uses non-targeted methods where the analytical conditions are optimized to detect and identify as many molecules as possible.
The reactor was placed for 2 h in the dark box to make the photocatalytic composite particles adsorb as many dye molecules as possible.
On the other hand, it is quite often that researchers would like to collect as much information about a molecule (or set of molecules) as possible, e.g. whether the compound is synthesizable or purchasable, its reported role in a biological system, a set of references for it, etc.
But, in optimal circumstances, it has become possible to detect electrons being in two places at one time: "if you pump out as many air molecules as possible with a good vacuum pump, an electron can typically survive for about a second without colliding with anything, which is plenty enough time for it to demonstrate funky quantum-superposition behavior" (p. 199).
We then investigated the role of other possible IL-1-induced molecules as possible mediators of IL-1 action.
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ENPOP iteratively adjusts the parameters simultaneously to move the model global minimum energy conformation for each of m different molecules as close as possible to the true native conformations, based on some appropriate measure of structural error.
To study the cellular receptor distribution after agonist exposure it is necessary to remove unspecifically bound molecules as completely as possible.
The probe itself should resemble the host matrix molecules as closely as possible to favour intercalation and cause minimal disruption to the phase, and the SP fragment itself must be orientationally rigid with respect to the discotic core.
As pointed out in a recent review by Scior et al.[53], because adequate conformational space coverage is an important requirement for reliable 3-D similarity computations, it would be desirable to consider as many conformations per molecule as possible.
In this brief review we will review a number of candidate molecules implicated as possible predictors of dementia risk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com