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Small molecules tend to diffuse into the interior of the porous particles so that their flow is restricted, while large molecules are unable to enter the pores and tend to flow unhindered.
(3) IgG4 molecules are unable to cross-link antigens due to Fab-arm exchange, and therefore, are unable to form immune complexes [8].
In contrast, if molecules are unable to transfer energy, no change in fluorescence of the FRET donor should be observed after bleaching.
Although most soluble CEA molecules are unable to mediate intercellular associations, C-CAM4 actively promotes cell adhesion (Lin et al. 1998).
Due to protein size and electrical charge, protein-bound molecules are unable to pass through the filter membranes and only unbound molecules will be available for elimination by CRRT.
It turns out that the mutant sodium channel mRNA molecules are unable to form RNA duplexes with potassium channel mRNA molecules: these duplexes would normally limit the number of potassium channels so, in their absence, the number of potassium channels increases, and this protects the flies from seizures.
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For example, the UDP-N-acetylglucosamine enolpyruvyl transferase enzyle enzyme (MurA, PDB code: 1uae) from E. coli exists in the PDB only as apoprotein and our initial docking study with the docking program FRED software [62] showed that most drug-like molecules were unable to dock in this binding site without exhibiting severe clashes with the amino acid residues.
However, evidence indicates that the expression of these non-translational machinery-related molecules is unable to fully explain how protein synthesis is regulated for memory consolidation [43], [44].
The result confirms that the fluorescent C12-resorufin molecules were unable to leak between emulsion compartments during the fluorescence generation incubation, and that C12-resorufin fluorescence generated by hydrogenase activity can be used to identify active enzymes.
Furthermore, preincubation of IFN-gamma treated breast cancer cells with F ab' 2 fragments of monoclonal antibodies to HLA class I and HLA class II molecules was unable to restore lysis.
Human saphenous vein SMCs expressing MHC class II molecules were unable to activate allogeneic memory T cells [ 18] and failed to effectively support T cell proliferation to the polyclonal activator, phytohemagglutinin [ 19].
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