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Large, multidomain RNA molecules are generally thought to fold following multiple pathways down rugged landscapes populated with intermediates and traps.
However, molecules are generally disinclined to adopt the desired structural organization because they behave according to their own specific intermolecular interactions.
It is shown that electrodiffusion processes of mobile ions and polarizable molecules are generally coupled among diffusion fluxes as well as with the polarization of the molecules.
This approach differs from classical quantitative structure activity relationship (QSAR) methods where molecules are generally described using vectors composed of descriptors.
Because larger molecules are generally more antigenic, the present objectives were to: (i) determine if plant profilin forms multimers; (ii) use the allergenic property of profilin in the design of an immunoassay to detect type I allergies in the local population; and (iii) assess the allergenic potential of monomeric versus multimeric profilin.
However, highly complex molecules are generally much less suitable as reference compounds for fingerprint searching than active compounds having complexity comparable to the screening database [5].
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Aging of drug molecules is generally studied following regulatory procedures, i.e. under forced conditions and for relatively limited storage time; therefore naturally aged samples are rare and provide scientific reference data beyond regulatory considerations.
When multiple queries are available, we find that a fingerprint averaged over all query molecules is generally superior to fingerprints derived from single queries.
All the animals in group 3 and 4 developed viremia detected by real time RT-PCR, but the onset of viremia was delayed, viremia lasted for a shorter period of time, and the number of FMDV RNA molecules was generally 103- to 104-fold lower than in the control animals.
On the other hand, achieving bright emission with NIR fluorescent molecules is generally much more difficult than with UV or visible chromophores and dyes.
The expression of MHC class II molecules is generally restricted to professional antigen-presenting cells, so as to regulate the initiation of responses by CD4+ T helper cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com