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In vivo, RNA molecules are constantly accompanied by RNA binding proteins (RBPs), which are intimately involved in every step of RNA biology, including transcription, editing, splicing, transport and localization, stability, and translation.
In a stationary liquid, individual molecules are constantly moving, and their motions are largely confined within a "cage" formed by the closely packed neighboring molecules [36].
Diffusion occurs because all molecules are constantly in motion colliding and exchanging energy with their neighbours.
However, as mRNA molecules are constantly produced, RNA-based approaches require repeated administration of the inactivating reagent.
As such, high quality, diverse and unique small molecules are constantly in demand in order to probe a wider range of new biological space.
Moreover, since RNA and protein molecules are constantly being expressed, their sustained inhibition requires continuous administration of inhibitors or potentially harmful integration of the (RNA interference) transgene expression cassette into the host genome.
Similar(54)
Mutant DNA molecules were constantly found to be equally distributed among the various blastomeres of a carrier embryo until day 5, in agreement with data on mtDNA polymorphisms achieved in mouse [Dean et al., 2003] and human embryos [Marchington et al., 2010], as well as on the m.8993T > G (NARP) mutation in human [Steffann et al., 2006].
Using our proprietary mRNA technology, coding and non-coding parts of the molecule are constantly modified by in silico and experimental methods to increase both the level and duration of protein expression.
The mucosal immune system of fish is a complex network of immune cells and molecules that are constantly surveilling the environment and protecting the host from infection.
While such protein switches are often depicted as static structures that are either on or off, in reality these proteins are active molecules that are constantly changing shape.
Reactant molecules in solution are constantly battered by solvent molecules, and these collisions ultimately destroy the coherence of the excited states necessary to actively control product formation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com